Publications

18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis

September 21, 2023

Liberman N, Rothi MH, Gerashchenko MV, Zorbas C, Boulias K, MacWhinnie FG, Ying AK, Flood Taylor A, Al Haddad J, Shibuya H, Roach L, Dong A, Dellacona S, Lafontaine DLJ, Gladyshev VN, Greer EL. 18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis. Mol Cell. 2023 Sep 21;83(18):3268-3282.e7. doi: 10.1016/j.molcel.2023.08.014. Epub 2023 Sep 8. PMID: 37689068.

Role of epigenetics in unicellular to multicellular transition in Dictyostelium

May 4, 2021

Wang SY, Pollina EA, Wang IH, Pino LK, Bushnell HL, Takashima K, Fritsche C, Sabin G, Garcia BA, Greer PL, Greer EL. Role of epigenetics in unicellular to multicellular transition in Dictyostelium. Genome Biol. 2021 May 4;22(1):134. doi: 10.1186/s13059-021-02360-9. PMID: 33947439; PMCID: PMC8094536.

N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance

April 22, 2020

Liberman N, O’Brown ZK, Earl AS, Boulias K, Gerashchenko MV, Wang SY, Fritsche C, Fady PE, Dong A, Gladyshev VN, Greer EL. N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance. Sci Adv. 2020 Apr 22;6(17):eaaz4370. doi: 10.1126/sciadv.aaz4370. PMID: 32494643; PMCID: PMC7176415.

Identification of the m⁶Am Methyltransferase PCIF1 Reveals the Location and Functions of m⁶Am in the Transcriptome

August 8, 2019

Boulias K, Toczydłowska-Socha D, Hawley BR, Liberman N, Takashima K, Zaccara S, Guez T, Vasseur JJ, Debart F, Aravind L, Jaffrey SR, Greer EL. Identification of the m⁶Am Methyltransferase PCIF1 Reveals the Location and Functions of m⁶Am in the Transcriptome. Mol Cell. 2019 Aug 8;75(3):631-643.e8. doi: 10.1016/j.molcel.2019.06.006. Epub 2019 Jul 3. PMID: 31279658; PMCID: PMC6703822.

Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

October 19, 2011

Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y, Brunet A. Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature. 2011 Oct 19;479(7373):365-71. doi: 10.1038/nature10572. PMID: 22012258; PMCID: PMC3368121.

Recent publications

• Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspring
  December 1, 2023
  Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspringAlata Jimenez, N., Castellano, M., Santillan, E. M., Boulias, K., Boan, A., Arias Padilla, L. F., Fernandino, J. I., Greer, E. L., Tosar, J. P., Cochella, L. & Strobl-Mazzulla, P. H., Dec 2023, In: Nature communications. 14, 1, 1617.Research output: Contribution to journal › Article › peer-review
• 18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis
  September 21, 2023
  18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesisLiberman, N., Rothi, M. H., Gerashchenko, M. V., Zorbas, C., Boulias, K., MacWhinnie, F. G., Ying, A. K., Flood Taylor, A., Al Haddad, J., Shibuya, H., Roach, L., Dong, A., Dellacona, S., Lafontaine, D. L. J., Gladyshev, V. N. & Greer, E. L., Sep 21 2023, In: Molecular cell. 83, 18, p. 3268-3282.e7Research output: Contribution to journal › Article › peer-review
• Prometheus unshackled: Liver regeneration makes you young
  May 18, 2023
  Prometheus unshackled: Liver regeneration makes you youngPollina, E. A. & Greer, E. L., May 18 2023, In: Molecular cell. 83, 10, p. 1546-1548 3 p.Research output: Contribution to journal › Comment/debate
• Inheritance of directed DNA cytosine methylation in mammals
  May 1, 2023
  Inheritance of directed DNA cytosine methylation in mammalsSarkar, G. & Greer, E. L., May 2023, In: Lab Animal. 52, 5, p. 105-107 3 p.Research output: Contribution to journal › Article › peer-review
• Biological roles of adenine methylation in RNA
  March 1, 2023
  Biological roles of adenine methylation in RNABoulias, K. & Greer, E. L., Mar 2023, In: Nature Reviews Genetics. 24, 3, p. 143-160 18 p.Research output: Contribution to journal › Review article › peer-review
• Deadly males accelerate aging with piRNAs
  January 1, 2023
  Deadly males accelerate aging with piRNAsGreer, E. L., Jan 2023, In: Nature Aging. 3, 1, p. 7-8 2 p.Research output: Contribution to journal › Comment/debate
• From correlation to causation: The new frontier of transgenerational epigenetic inheritance
  January 1, 2023
  From correlation to causation: The new frontier of transgenerational epigenetic inheritanceRothi, M. H. & Greer, E. L., Jan 2023, In: BioEssays. 45, 1, 2200118.Research output: Contribution to journal › Article › peer-review
• Hypoxia induces transgenerational epigenetic inheritance of small RNAs
  December 13, 2022
  Hypoxia induces transgenerational epigenetic inheritance of small RNAsWang, S. Y., Kim, K., O'Brown, Z. K., Levan, A., Dodson, A. E., Kennedy, S. G., Chernoff, C. & Greer, E. L., Dec 13 2022, In: Cell Reports. 41, 11, 111800.Research output: Contribution to journal › Article › peer-review
• Means, mechanisms and consequences of adenine methylation in DNA
  July 1, 2022
  Means, mechanisms and consequences of adenine methylation in DNABoulias, K. & Greer, E. L., Jul 2022, In: Nature Reviews Genetics. 23, 7, p. 411-428 18 p.Research output: Contribution to journal › Review article › peer-review
• Multigenerational epigenetic inheritance: Transmitting information across generations
  July 1, 2022
  Multigenerational epigenetic inheritance: Transmitting information across generationsBurton, N. O. & Greer, E. L., Jul 2022, In: Seminars in Cell and Developmental Biology. 127, p. 121-132 12 p.Research output: Contribution to journal › Review article › peer-review